- I-81 is the longest interstate in Virginia and rated one of the top eight truck routes in the U.S.
- I-77 connects the eastern Great Lakes region with Appalachia and the Southeast.
- The region also offers access to I26 (16 miles), I64 (31 miles), and I40 (37 miles), as well as four-lane highway systems, including U.S. 460, U.S. 58, and U.S. 23, stretching from Virginia to Detroit.
- Freight rail service is provided by Norfolk Southern, offering a wide range of reliable and efficient shipping options.
- The Virginia TradePort, located at the New River Valley Airport in Dublin, is approximately 32 miles north.
- Three airports in the region provide general aviation services, and a few major airports with international connections are a short drive away, including Tri-Cities Regional Airport (TRI – 21 miles).